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Biotech News

Original reporting and analysis on the stories shaping biotech.

Clinical & Regulatory5 min read

BMS Bet $800M on a Chinese Cancer Drug. It Just Paid Off.

Bristol Myers Squibb paid $800 million for a cancer drug from a Chinese biotech nobody was watching. It just hit both survival endpoints in the toughest form of breast cancer, marking the first time a bispecific ADC has pulled off that feat. The $8.4 billion bet is starting to look like a bargain.

Mar 1, 2026Read article
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Deals & M&A5 min read

Merck's $33 Billion Problem Has a New Battle Plan

Merck is splitting its pharma business in two as it stares down the expiration of Keytruda's patent, the world's best-selling drug at nearly $30 billion in annual sales. It's one of Big Pharma's boldest reorganizations in years, and the clock is ticking toward 2028.

Mar 2, 2026
Clinical & Regulatory5 min read
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The $2.9 Million Drug Nobody Wanted to Buy

BioMarin is pulling its $2.9 million hemophilia gene therapy Roctavian from the market after failing to find a single buyer. Combined with Pfizer's identical retreat from its own hemophilia gene therapy, it raises a billion-dollar question: can one-time cures ever make money?

Mar 2, 2026
Science & Discovery4 min read

Viruses Found the One Weak Spot in Superbugs. Now Scientists Want to Steal It.

Three completely unrelated viruses independently figured out how to kill bacteria by attacking the same protein. Caltech scientists think this viral trick could unlock an entirely new class of antibiotics against drug-resistant superbugs.

Mar 1, 2026
Science & Discovery4 min read

Cambridge Scientists Built Tiny Rooms Inside Bacteria. Here's Why It Matters.

Cambridge researchers engineered self-assembling RNA "nanostars" that build programmable compartments inside bacteria for the first time. The implications for how we manufacture therapeutic proteins could be enormous.

Mar 1, 2026
Funding & Financings4 min read

The $130M Bet That CGRP Isn't the Only Way to Fight Migraines

A brand-new biotech just launched with $130 million to target migraines through a completely different pathway than every existing preventive drug. For patients who don't respond to CGRP therapies, Slate Medicines might be building the backup plan they've been waiting for.

Mar 1, 2026
Clinical & Regulatory5 min read

Dupixent's Ninth Life: The Drug That Won't Stop Collecting FDA Approvals

Dupixent just landed its ninth FDA approval, this time as the first-ever drug for allergic fungal rhinosinusitis. The trial data is staggering: a 92% reduction in the need for surgery or steroids. For patients stuck in a brutal cycle of repeat sinus surgeries, everything just changed.

Mar 1, 2026
Clinical & Regulatory5 min read

The Senate Just Called the FDA a "Roadblock." Rare Disease Biotechs Are Watching.

The Senate titled its FDA hearing "From Regulator to Roadblock" and brought in biotech CEOs and patient advocates to make the case. With fresh legislation already reshaping orphan drug exclusivity and a $243 billion market at stake, rare disease biotechs are paying very close attention.

Feb 27, 2026
Science & Discovery5 min read

What If Psychedelics Worked Without the Trip?

A new biotech called Five Discovery wants to give your brain the healing power of psychedelics without the hallucinations. They're not alone in the race, and the science behind it is surprisingly compelling.

Feb 27, 2026
Deals & M&A5 min read

AbbVie Just Dropped $650M on a Cancer Drug That Doesn't Exist Yet

AbbVie wired $650 million to Chinese biotech RemeGen for a cancer drug still in phase 2 trials, with the total deal potentially worth $5.6 billion. It's a massive bet that bispecific antibodies will reshape oncology, and AbbVie isn't the only one racing to find out.

Feb 27, 2026
Clinical & Regulatory4 min read

Novo's Triple Threat Obesity Drug Just Entered the Ring

Novo Nordisk's Triple G obesity drug just posted nearly 20% weight loss in 24 weeks, adding a metabolic twist that existing drugs don't have. But with Lilly's retatrutide already showing 29% in trials, the real fight is just getting started.

Feb 27, 2026
Deals & M&A6 min read

The $885M Bet on Biotech's Hottest Spare Part

Earendil Labs just signed an $885 million deal with WuXi XDC for linker technology, the unglamorous connector that holds cancer-killing ADCs together. In biotech's hottest arms race, the most valuable weapon might be the glue.

Feb 27, 2026
Deals & M&A4 min read

Gilead Just Paid $7.8B for a Protein the Size of a Paperclip

Gilead is spending $7.8 billion to acquire Arcellx and its next-gen CAR-T therapy for multiple myeloma. The secret weapon? A synthetic protein one-third the size of what competitors use, with clinical data that might just be best-in-class.

Feb 27, 2026
Deals & M&A4 min read

Novartis Spent $12B on Avidity. The Leftovers Just Raised $270M.

Novartis paid $12 billion for Avidity Biosciences but left the cardiology programs on the table. Those "leftovers" just launched as Atrium Therapeutics with $270 million and two preclinical heart disease drugs. Sometimes the best biotechs are built from what big pharma didn't want.

Feb 27, 2026
Sarepta's Most Polarizing CEO Is Walking Away. Here's What He Left Behind.
Clinical & Regulatory4 min read

Sarepta's Most Polarizing CEO Is Walking Away. Here's What He Left Behind.

Sarepta's Doug Ingram is retiring after a decade of FDA battles, gene therapy breakthroughs, and an 82% stock collapse. His departure, driven partly by his own family's muscular dystrophy diagnosis, leaves behind one of biotech's most complicated legacies.

Feb 26, 2026
GSK Just Paid $950M for a Drug That Doesn't Exist Yet
Deals & M&A5 min read

GSK Just Paid $950M for a Drug That Doesn't Exist Yet

GSK is paying $950 million in cash for a Canadian startup whose lead drug has never been tested in a single patient with pulmonary hypertension. The science behind the deal, and the market it's chasing, might explain why.

Feb 26, 2026
Biotech's Pink Slip Problem Just Got 3,200 Names Longer
Deals & M&A4 min read

Biotech's Pink Slip Problem Just Got 3,200 Names Longer

Viatris beat earnings expectations and landed an analyst upgrade, then announced 3,200 job cuts. With at least 18 companies slashing headcount in early 2026, biotech's layoff wave isn't slowing down. It might be the new normal.

Feb 26, 2026
BMS Just Won Its Biggest Bet in Years, and It Cost $8.4 Billion
Clinical & Regulatory4 min read

BMS Just Won Its Biggest Bet in Years, and It Cost $8.4 Billion

Bristol Myers Squibb's $8.4 billion ADC bet just cleared its biggest hurdle yet, hitting both survival endpoints in a Phase 3 trial against one of cancer's most ruthless forms. The full numbers aren't out yet, but what we know so far has major implications for TNBC patients and the red-hot ADC market.

Feb 26, 2026
Novo Nordisk's $2.1B Bet That the Future of Weight Loss Is a Pill
Deals & M&A4 min read

Novo Nordisk's $2.1B Bet That the Future of Weight Loss Is a Pill

Novo Nordisk just dropped $2.1 billion on a tiny MIT spinout to crack oral biologic delivery for obesity drugs. With Eli Lilly's oral GLP-1 already beating Novo's in head-to-head trials, this might be the most important bet the Danish pharma giant has ever made.

Feb 26, 2026
A Chemical Company Just Dropped $920M on an Antiviral Biotech. Wait, What?
Deals & M&A5 min read

A Chemical Company Just Dropped $920M on an Antiviral Biotech. Wait, What?

A Japanese chemicals-and-housing conglomerate just dropped $920 million on a German antiviral biotech. It sounds absurd — until you look at what Asahi Kasei has been quietly building for the last 50 years.

Feb 26, 2026
Half a Billion for a Pill That Doesn't Exist Yet
Deals & M&A4 min read

Half a Billion for a Pill That Doesn't Exist Yet

Boehringer Ingelheim just dropped $500 million on a preclinical pill from a tiny Oxford biotech, and it's not the only massive immunology deal they've inked lately. The race to replace autoimmune injections with oral therapies is getting very expensive, very fast.

Feb 26, 2026
The Cancer Target That Fought Back
Clinical & Regulatory4 min read

The Cancer Target That Fought Back

Accent Therapeutics killed its entire DHX9 inhibitor program after safety concerns torpedoed its first-in-human cancer trial. The setback raises tough questions about whether RNA helicases (one of oncology's most tantalizing target families) can ever be safely drugged.

Feb 26, 2026